They signed one-half of the pair, Billy Sharp, on Wednesday, breaking their record transfer signing as they paid Sheffield United £1.15million for his services.
Now they have targeted the signing of Andy Keogh, 24, who the Premier League side Wolves are believed to be willing to offload him.
"To put Andy and Billy together again is something to consider. You talk to a lot of clubs about players without making a concrete offer and we've done that with Andy," said Sean O'Driscoll, the Doncaster manager.
"It will all depend on what Andy's situation is with Wolves. He knows a lot of our players and he certainly interests us."
Mick McCarthy, the Wolves boss, confirmed he will be reducing his squad to comply with new regulations which limit the number of players over 21 he can have to 25.
"I'm going to have to say to some of them 'listen, there's two weeks to go and you're not going to be in my squad'. I will be totally fair to them. I won't leave it until the last knock-ins. I'll tell them their futures will be sorted out a lot sooner than that," he said.
"Don't get me wrong, I love all the lads and I've got respect for them all. But the last thing I want is anyone left here from the end of August until January who can't play."
Sharp, also 24, has spoken to Keogh informally and the Irishman is interested in a move to secure first-team football.
Keogh scored seven goals before being sold to Wolves in January of United's League One-winning campaign, while Sharp was the main goalscorer with 32 coming by the end of the season.
Sharp followed Keogh out the exit door at Glanford Park that summer, signing for his boyhood club Sheffield United in a deal with £2m.
One stumbling block for Doncaster may be the interest of other Championship clubs, while Rovers are seeking a loan move the Midlands club may be more willing to listen to offers for a permanent move - with Leeds United and Barnsley both believed to be trailing him.