One of those sides are 'fallen giants' Nottingham Forest, who followed up their opening day win with a 3-2 loss at Walsall.
It leaves the Saddlers joint top with Oldham, who ran out 3-2 victors at Swindon, and Swansea, who won 2-1 at Colchester.
Those results leave Swindon bottom, just below Colchester on goal difference
Of the clubs newly-promoted from League Two, champions Yeovil are the only side yet to win - they drew 0-0 with Rotherham at Huish Park.
Southend pulled off an impressive 2-0 win at Bradford City.
Pawel Abbott hit an 89th minute equaliser to fire Huddersfield to a single goal victory over Bristol City.
Blackpool fought back to draw 2-2 at Tranmere, while Doncaster Rovers were held 1-1 by MK Dons.
Gillingham and Port Vale played out a goalless draw, leaving them in fourth and fifth respectively.
Brentford travel up the A1 to play Chesterfield on Wednesday evening.