A brace from Andy Keogh, coupled with strikes from Peter Beagrie and Matty Sparrow sealed the win which moved the Iron onto 14 points from their opening seven games.
Dean Windass showed off exactly why Premiership side Wigan tried to sign him before the transfer deadline, as he helped Bradford to a 2-0 win over Chesterfield.
He scored after 75 minutes, with Marc Bridge-Wilkinson adding the second.
Blackpool pulled away from the relegation zone with a 1-0 win at Doncaster Rovers - with Ciaran Donelly getting the only goal of the game.
Bournemouth and Tranmere played out a goalless draw at Dean Court.
With World Cup qualifiers on Saturday, the League One fixtures are spread out over the weekend.
United could be knocked off the top spot on Saturday. Fixtures to come:
Saturday: Bristol City v Colchester, Hartlepool v Yeovil, Nottm Forest v Brentford, Port Vale v Rotherham, Walsall v Swindon.
Sunday: Southend v Oldham.