Blackpool: Ian Evett is ruled out with a hamstring injury, Kaspar Gorkss is likely to deputise.
Bristol City: Winger Ivan Sproule is suspended. Goalkeeper Adriano Basso should be fit despite suffering a rib injury against QPR on the opening day of the season.
Betting: H 11-10 A 2-1 D 11-5
Referee: C Webster (Tyne & Wear)
Colchester v Barnsley (Layer Road, 3pm)
Colchester: Kevin Lisbie (ankle) and Jamie Guy (thigh) are doubts. Striker CLive Platt starts a three-game ban.
Bristol City: Kim Christensen will go straight into the Tykes squad.
Betting: H 5-6 A 11-4 D 11-5
Referee: A Hall (W Midlands)
Crystal Palace v Leicester City (Selhurst Park, 3pm)
Palace: Ben Watson is ruled out with ankle ligament damage.
Leicester: Patrick Kisnorbo returns from suspension, while Clive Clarke and Marton Fulop will make their first appearances in the squad. James Chambers (calf) and Darren Kenton (ribs) are doubts.
Betting: H 21-20 A 21-10 D 11-5
Referee: M Russell (Hertfordshire)
Coventry City v Hull City (Ricoh Arena, 3pm)
Coventry: Defender David McNamee (calf) will miss out.
Hull: The Tigers have a full squad to choose from.
Betting: H 8-11 A 16-5 D 9-4
Referee: B Knight (Kent)
Norwich City Southampton (Carrow Road, 3pm)
Norwich: Adam Drury (ankle) is ruled out, with Simon Lappin likely to deputise at left-back. Julien Brellier (back) is out.
Southampton: New signing Wayne Thomas is in line for a debit. Darren Powell is banned, while Claus Lundekvam is out with an ankle injury. Inigo Idiakez returns from a hamstring injury.
Betting: H 13-10 A 7-4 D 21-10
Referee: C Oliver (Northumberland)
Plymouth Argyle v Ipswich Town (Home Park, 3pm)
Plymouth: Ian Holloway has no major injury concerns
Ipswich: Richard Naylor misses out after going under the knife for a toe problem. Gavin Williams and Dean Bowditch are long term absentees.
Betting: H 5-4 A 7-4 D 11-5
Referee: K Friend (Leicestershire)
QPR v Cardiff City (Loftus Road, 3pm)
QPR: Dexter Blackstock (hamstring) and Daniel Nardiello (back) return to contention.
Cardiff: Robbie Fowler is out, while new signing Jimmy Flloyd Hasselbaink will not join up with his new team-mates in time.
Betting: H 13-10 A 13-8 D 11-5
Referee: P Joslin (Nottinghamshire)
Stoke City v Charlton (Britannia Stadium, 3pm)
Stoke: Danny Higginbotham (ankle) will have a late fitness test.
Charlton: Luke Varney is out with an ankle injury. Zheng Zhi and Therry Racon are in contention for their debuts, while Jerome Thomas has also returned to full fitness.
Betting: H 7-5 A 8-5 D 21-10
Referee: G Laws (Tyne & Wear)
Watford v Sheffield United (Vicarage Road, 3pm)
Watford: After naming a second string squad for the Carling Cup first round win over Gillingham, the Hornets will revert to a first-choice side.
Sheff U: Lee Hendrie is ruled out for two months with cartilage damage, while Gary Naysmith has a knee injury. Centre-back Chris Morgan returns following a calf strain.
Betting: H 23-20 A 19-10 D 11-5
Referee: Andre Marriner (W Midlands)
West Brom v Preston North End (The Hawthorns, 3pm)
WBA: Ishmael Miller will make his debut after joining on loan from Manchester City during midweek, but fellow newboy Chris Brunt sits out through suspension. Midfielder Richard Chaplow is a doubt with a foot problem.
Preston: Paul Simpson may hand a first start to on-loan Newcastle striker Andy Carroll, after giving him three minutes in the Carling Cup loss to Morecambe on Tuesday night.
Betting: H 4-5 A 14-5 D 9-4
Referee: M Jones (Cheshire)
