The Black Cats, who won the Championship title this season, will visit Glanford Park on Saturday July 21.
United will also host a game the following Saturday, though the opponent has yet to be confirmed.
The final friendly of the summer will see the Iron travel to local rivals Grimsby Town on Saturday August 4.
There are likely to be traditional trips to local non-league sides Brigg Town and Winterton Rangers, though dates have not been announced.
In addition to these friendlies, Scunthorpe will have two Lincolnshire Senior Cup games to play.
Bizarrely this season's final, against Lincoln, will be played after next season's semi-final.
The Iron will travel to Lincoln on Wednesday August 1 looking to win the silverware.
But the previous Wednesday, July 25, they will have met Boston United in next year's competition.