Sharp has now fully recovered from ankle ligament injury, and after a string of cameo appearances off the bench should partner fellow teenager Andy Keogh up front.
Scunthorpe will again be without midfielder Matty Sparrow – who serves the second and final game of a suspension. It means Cleveland Taylor will continue to deputise on the right wing.
Yeovil are waiting on the fitness of dfender Kevin Amankwaah – who missed last weekend's 3-0 win over Doncaster with an ankle injury.
Striker Daniel Webb is also struggling with a similar problem.
Yeovil boss Steve Thompson has called on his side to build on last week's impressive win over Doncaster – a win on Friday night would see the Glovers move level on points with the Iron.
He said: "It was great win against Doncaster but now we need to go and do it all again against Scunthorpe.
"It's another massive home match for us and important we get the supporters in and behind us again – they were fantastic against Doncaster."