If Keogh misses the Port Vale game the Iron will only have Steve Torpey, Tommy Johnson and Andy Parton available for action as Billy Sharp faces a long injury lay-off with ligament damage.
He sat out last week's home defeat to Bristol City to play in two games for the Republic against Madeira and Finland respectively but he rushed back to Scunthorpe ahead of the Swansea game, missing Ireland's final victory over Portugal.
Cruelly he contracted food poisoning after returning to the United Kingdom and could only come on as a substitute in the Swans game after being continuously sick 24 hours beforehand.
"We had a great week of football in Madeira, the professionalism the squad showed both on and off the pitch was second to none and the quality of football was extremely high," said boss Don Givens.
"We need to build on this in preparation for our preliminary rounds for the European championships and this game against Sweden will begin our journey."
The Irish squad in full: Darren Quigley (UCD), Colin Doyle (Millwall), Kevin Foley (Luton Town), Paul McShane (Brighton & Hove Albion), Marcos Painter (Birmingham City), Alex Bruce (Birmingham City), Richard Keogh (Bristol City), James Hand (Huddersfield Town), Willo Flood (Manchester City), Gary Dicker (UCD), Darren Potter (Southampton), Glenn Whelan (Sheffield Wednesday), Michael Timlin (Fulham), Roy O'Donovan (Cork City), Jay Tabb (Brentford), Stephen Ward (Bohemians), Andy Keogh (Scunthorpe United), Leon Best (Sheffield Wednesday)