And although he started against Burnley last Saturday, he had to be replaced with Andy Butler early in the second-half.
Butler put in a superb performance, and may even keep his place regardless of whether Iriekpen proves his fitness in training on Friday.
Scunthorpe have no fresh injury concerns, with only long-term absentee Ian Morris also out of action.
The Republic of Ireland U-21 international suffered a posterior cruciate ligament injury in pre-season, and is still in a leg brace.
Bristol City were promoted to the Championship along with Scunthorpe this summer, after finishing second in League One.
Gary Johnson's side will be without Northern Ireland winger Ivan Sproule, as the former Hibs man continues a suspension he picked up in the Scottish Premier League before his summer move to Ashton Gate.