In fact, only Chesterfield and Southend are considered less likely to win the League than the Iron.
But boss Brian Laws will be hoping the pessimistic odds are a good omen - United finished second in the table after being tipped to finish second bottom by the bookies.
Nottingham Forest are 5/2 favourites to win the title, followed closely by Tranmere Rovers - who narrowly missed out on automatic promotion this term - at 9/2, and Bristol City at 13/2.
Odds to win promotion or to be relegated are not yet available - though it is a safe bet that they will back United to be among the sides in the relegation battle.
In League Two, Northampton are 6/1 title favourites ahead of Darlington at 7/1.
Lincoln, play-off final losers, are rated at 12/1, while the Cods are 20/1 long shots.
Bet365 odds to win League One in full:
Nottm Forest 9/2
Tranmere 13/2
Bristol City 9/1
Hartlepool 10/1
Gillingham 12/1
Walsall 12/1
Barnsley 14/1
Huddersfield 14/1
Oldham 16/1
Rotherham 16/1
Bournemouth 20/1
Brentford 20/1
Yeovil 20/1
Bradford 22/1
Doncaster 22/1
MK Dons 25/1
Swindon 25/1
Blackpool 28/1
Colchester 33/1
Port Vale 33/1
Swansea 33/1
Scunthorpe 40/1
Chesterfield 50/1
Southend 50/1