Bolton Wanderers striker Tope Obadeyo hit a hat-trick, as Brian Eastick's side outclassed the visitors at Scunthorpe's Glanford Park stadium.
They took the lead in only the second minute, with Ciaran Clark heading home from James Henry's corner.
Obadeyi doubled the Young Lions' advantage with 30 minutes ont he clok when he tapped the ball home following a fumble from Romania keeper Alexandru Oprea.
And England had a 3-0 advantage at the break when Jamie Chandler smashed the ball home from Kieran Gibbs' square ball.
The home side were troubling the scoreboard again just four minutes after the restart.
Chelsea midfielder Jack Cork, playing on his home ground as he is on-loan at Championship surprise package Scunthorpe, played in Febian Brandy to score at the far post.
Having conceded four goals Romania swopped keepers, with Mirel Bolboasa coming on in place of Oprea.
The new boy was to be beaten twice, with Obayeyi getting his second of the match on 70 minutes and completing his hat-trick in the closing stages.
Having beaten Iceland 5-0 at Doncaster on Friday night, Eastick's side are guaranteed progression to the second qualifying round - with a place in next summer's final in the Czech Republic tantalisingly close.
The Young Lions draw their preliminary round campaign to a close on Wednesday night, when they meet Belgium at Barnsley's Oakwell stadium.
They took the lead in only the second minute, with Ciaran Clark heading home from James Henry's corner.
Obadeyi doubled the Young Lions' advantage with 30 minutes ont he clok when he tapped the ball home following a fumble from Romania keeper Alexandru Oprea.
And England had a 3-0 advantage at the break when Jamie Chandler smashed the ball home from Kieran Gibbs' square ball.
The home side were troubling the scoreboard again just four minutes after the restart.
Chelsea midfielder Jack Cork, playing on his home ground as he is on-loan at Championship surprise package Scunthorpe, played in Febian Brandy to score at the far post.
Having conceded four goals Romania swopped keepers, with Mirel Bolboasa coming on in place of Oprea.
The new boy was to be beaten twice, with Obayeyi getting his second of the match on 70 minutes and completing his hat-trick in the closing stages.
Having beaten Iceland 5-0 at Doncaster on Friday night, Eastick's side are guaranteed progression to the second qualifying round - with a place in next summer's final in the Czech Republic tantalisingly close.
The Young Lions draw their preliminary round campaign to a close on Wednesday night, when they meet Belgium at Barnsley's Oakwell stadium.
For more information on the England sides at all levels, including all the build-up to Wednesday's Euro 2008 qualifier against Russia, check out www.England-MAD.co.uk